This post may contain affiliate links. It is also used to prevent flea-allergy dermatitis (an allergy reaction to flea bites). We do this to improve browsing experience and to show personalized ads. As of July 1, 2018, the Merck Animal Health division of Merck & Co., Inc. has discontinued manufacture and sales of ACTIVYL (indoxacarb) Topical Solution for Cats. 6.Activyl vs. Revolution Comparison | PetMeds, 7.Activyl for Cats over 4kg Dark Blue 6s **DISCONTINUED, 8.The 5 best flea treatments for cats, with advice from veterinarians, 9.Is Activyl for Cats Discontinued? It provides 4 weeks of protection. No. Third, the discontinuation of Activyl will likely lead to an increase in the number of abandoned and feral cats. "When used as directed, ACTIVYL has been shown to kill fleas before they lay eggs for a full month and beyond, 2 which means the product more effectively controlled flea reproduction, and as a. A. Activyl for Dogs can be administered as early as 8 weeks of age. Learn More: What to do for cat with a cold? Bioactivation occurs when the cat eats the product or gets it in their system through exposure to the environment. Some of our partners may process your data as a part of their legitimate business interest without asking for consent. Isoxazoline products have been associated with neurologic adverse reactions, including muscle tremors, ataxia, and seizures in some dogs and cats; Although most dogs and cats havent had neurologic adverse reactions, seizures may occur in animals without a prior history; Many products are available for prevention and control of flea and tick infestations. Second, the increase in flea infestations will also impact wildlife. Activyl Protector Band for Dogs Achieve long lasting, water-resistant flea and tick control that also repels mosquitoes for up to 6 months with this no-mess and easy to apply solution. Hypothyroidism occurs when the thyroid glands become underactive and don't produce enough of the hormones typical of the thyroid. Is Activyl safe for dogs? Not sure why it was discontinued. Some of these alternatives include: BRAVECTO Topical Solution for Cats provides 12 weeks of protection against fleas and ticks in a single, easy-to-apply dose. His recommendations: Bravecto, NexGard and Simparica. There are several reasons that some cat owners choose not to use activyl for cats. Cats that are used to receiving regular doses of activyl may experience a sudden change in their energy levels and behavior. Once inside the body, Activyl works by bioactivation, a mode of action that changes the chemical into a highly insecticidal substance. Fleas on cats ingest indoxacarb as they feed, so it is effective throughout their body. There are a number of potential side effects associated with using Activyl for cats. Ticks can be found right in your own backyard. The technical storage or access is necessary for the legitimate purpose of storing preferences that are not requested by the subscriber or user. info About GoodRx Prices. If your dog or cat experiences any adverse event while using an isoxazoline product, first consult your veterinarian. The active ingredient in FRONTLINE (fipronil) kills fleas by affecting their nervous system, making them hyperactive before dying. It delivers 4 weeks of efficacy against adult fleas on the pet and developing stages of fleas in the pets environment. Activyl is easy and convenient to apply and it is fragrance-free. In some cases, cats may become lethargic and stop using the litter box. This new product works by being activated by only the flea's enzyme systems into a flea specific mechanism which paralyzes and kills the adult flea. Learn More: How to make your cat a lap cat? These include vomiting, diarrhea, loss of appetite, and increased thirst. This post may contain affiliate links. Treatment of existing infestations is also important to prevent the spread of fleas to humans and other animals. Drug Info. 160 Views. Sadly Activyl topical flea product is being discontinued due to storm damage. It blocks the sodium current amplitude in the neuron differently than the pyrethroids. The ingredients isopropyl alcohol and indoxacarb are both human-safe, so pets will not be harmed if the product is accidentally ingested. This enzymatic cleavage occurs in insects but not mammals. Get the facts, learn how to check for fleas and find the best treatment options for your dog. The technical storage or access is strictly necessary for the legitimate purpose of enabling the use of a specific service explicitly requested by the subscriber or user, or for the sole purpose of carrying out the transmission of a communication over an electronic communications network. In addition to being toxic, this product does not kill the targeted insects before they have a chance to transmit any diseases they may be carrying. Please take a look at other Flea & Tick available. 205 Views. It was especially popular among cat owners because it was one of the few products that was effective against both fleas and ticks. Once inside the fleas gut, the pesticides enzymes activate and kill the flea. Can changing cat litter brand make cat sick? ACTIVYL Dogs Product Description ACTIVYL for Dogs and Puppies is a once-a-month topical flea treatment for dogs and puppies over 4 lbs and 8 weeks of age and older. Any action you take based on the information found on nahf.org is strictly at your discretion. Its a small, liver-flavored chewable tablet available by prescription. The lawsuit, filed in the U.S. District Court of California in Los Angeles, comes just days after a congressional subcommittee asked Elanco to voluntarily recall the flea and tick collars in the wake of reporting by the Midwest Center for Investigative Reporting and USA TODAY on thousands of incident reports about pet and human harm linked to the collar. What is the safest most effective flea treatment for Dogs? If you suspect it is not controlling your pets fleas, you may, in certain cases, be able to reapply it in as little as two weeks and try again. Research ticks in your area, tick-borne diseases, how to help prevent ticks in your home and what to do if you find a tick on your dog. supply)? Activyl ships by ground only due to Department of Transportation . by Unfortunately, the manufacturer that produces Activyl flea preventative will no longer be making this product and is being discontinued from their line of flea products. This breaks the flea life cycle and keeps your home and your pets safe from fleas. Now that Activyl is being discontinued, pet owners will have to find a new product to protect their cats from fleas and ticks. What is Activyl used to prevent in dogs? Cytopoint Lawsuit? Another possibility is that there was some safety issue with the product that led to its discontinuation. It is important for cat owners to be aware of the risks and to take steps to protect their pets to the best of their ability. The contents of one full Activyl pipette (appropriate to the animal and its weight) is applied directly to the skin, after parting the animals fur, onto the . on dogs. Just lukewarm water, or water and a mild soap, can help get fleas off your pets fur and skin. Finally, discontinuing use of Activyl may cause increased stress levels in both cats and their owners. The two main ingredients are: Imidacloprid attacks the fleas nervous system and ultimately kills it. Zhao X, Ikeda T, Yeh JZ, Narahashi Y. Neurotoxicology 2003;24:8396. We and our partners use data for Personalised ads and content, ad and content measurement, audience insights and product development. How do you get rid of fleas on a big dog? We are stocked up currently, but once it's gone its gone. This will not only be devastating for the cat owners, but also for the cats themselves. The company consulted with key opinion leaders in the veterinary community and conducted market research to better understand why activyl sales were declining. When tested for a 2-month application period, *BRAVECTO kills fleas and prevents flea infestations for. Some of these products are used monthly, while others are used less often. K9 Advantix II. Manage Settings Activyl is used to treat and prevent flea infestations in dogs and cats and to treat flea-allergy dermatitis (an allergic reaction to flea bites). choices for flea and tick products, as well as heartworm prevention products. Activyl breaks down rapidly in the environment and does not accumulate in plants or animals. Activyl stops flea feeding, followed by paralysis and death after exposure to product. Activyl is a monthly spot-on product used to kill fleas. The FDA continues to monitor adverse drug event reports for these products and encourages pet owners and veterinarians to report adverse drug events. About seven days later, he starting having these aggressive outbursts, then acts overly sweet after. The consent submitted will only be used for data processing originating from this website. Activyl for . Please read ourdisclosure. Why Is My Cat Coughing Fits, Worms & Hairball. Flea treatment is a big business, and the loss of one of the most popular products will undoubtedly have an impact. Advertisement. Is Activyl better than frontline? What flea medicine is better than frontline? Why are fleas still alive after frontline? It is well tolerated by dogs and puppies. PRODUCT LABEL What makes Activyl flea treatment different? [Answer + Alternatives], Vitamin E Oil for Dogs: Dosage for Skin, Warts & Dry Nose. Some are also approved for treatment and control of ear mite infestations and some gastrointestinal parasite infections, and a few are also approved for prevention of heartworm disease. It takes Activyl 12 hours to kill adult fleas and 8-12 hours to kill newly arriving fleas. This decision will have a significant impact on the environment, as Activyl was one of the most popular and effective treatments for flea infestations in cats. The kill window for flea spray is around 12 hours. Trifexis employs spinosad and milbemycin oxime to keep dogs protected from heartworms and intestinal parasites as well as fleas, but it does not work against ticks. Activyl Tick Plus is not available. Short- and long-term adverse health and environmental consequences can be avoided. In terms of competition, there are several products on the market that are similar to activyl, including Frontline Plus, Advantage II, and Revolution. NexGard Soft Chew for Dogs is our top pick because of its effective, fast-acting main ingredient, low-maintenance dosage, and chewable formula. It can strip oils from your pets fur and dry out their skin. This is because the medication kills not only parasites, but also good bacteria that live on the skin and in the gastrointestinal tract. These products are approved for the treatment and prevention of flea infestations, and the treatment and control of tick infestations. Ticks, and the disease organisms they carry, including Lyme disease, are found all over the United States. From Johnathan Hettinger, Midwest Center for Investigative Reporting, March 26: Two pet owners who claim their dogs either died or developed problems after using Seresto flea and tick collars filed a class-action lawsuit this week against Elanco Animal Health, alleging it misrepresented the safety of its product. Did Brazil make it to the 2022 World Cup? The indoxacarb in Activyl is bioactivated in the flea by enzymatic N-decarbomethoxylation changing it to a more active, highly insecticidal metabolite.1. Unlike insects, mammals mostly metabolize indoxacarb into nontoxic metabolites. Learn More: What is the purpose of deworming cats? Unlike Frontline, it does not kill ticks. Descriptions: Yes, Activyl for cats and dogs has been discontinued by the manufacturer. In some cases, cats may also experience seizures or other neurological problems.